Pharmacology: Glucocorticoids cause profound and varied metabolic effects as well as modify the body's immune response to diverse stimuli. Naturally occurring glucocorticoids (Hydrocortisone and Cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs are primarily used for their potent anti-inflammatory effects in disorders of many organ systems. Triamcinolone differs from naturally occurring glucocorticoids by having a greater anti-inflammatory and gluconeogenic effect and diminished salt retaining properties.
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